Palonosetron HCl( Purity > 99% by HPLC)

Product Name: Palonosetron HCl
 CAT#: A-2170

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 Synonym:RS 25233-197; RS25233-197; RS-25233-197; RS25233-198; RS-25233-198; RS 25233-198; RS-25259-197; Palonosetron hydrochloride; Palonosetron HCl, US brand name: Aloxi. ,

Palonosetron HCl Chemical Structure
Palonosetron HClchemical structure

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IUPAC/Chemical name:

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Biological Activity
Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is used for the control of delayed CINV—nausea and vomiting and there are tentative data to suggest that it may be better than granisetron. Palonosetron is administered intravenously, as a single dose, 30 minutes before chemotherapy, or as a single oral capsule one hour before chemotherapy. The oral formulation was approved on August 22, 2008 for prevention of acute CINV alone, as a large clinical trial did not show oral administration to be as effective as intravenous use against delayed CINV.
Technical Data

Purity: >99%
CAS#: 135729-62-3
Chemical Formula:C19H25ClN2O
Molecular Weight:332.87
Palonosetron HCl MSDSPalonosetron HCl CoA

IUPAC/Chemical name:(R)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride
Canonical SMILES:
Reference





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