Peplomycin( Purity > 99% by HPLC)

Product Name: Peplomycin
 CAT#: A-2177

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 Synonym: pepleomycin. Abbreviation: PEP. Chemical structure names: * (S)-n1-[3-[(1-phenylethyl)amino]propyl]bleomycinamide. * n1-[3[[(S)-alpha-methylbenzyl]amino]propyl]bleomycinamide. ,

Peplomycin Chemical Structure
Peplomycinchemical structure

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IUPAC/Chemical name:

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Biological Activity
A semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Peplomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single- and double-stranded breaks in DNA. This agent appears to show greater antitumor activity than bleomycin; its use is limited due to pulmonary toxicity.
Technical Data

Purity: >99%
CAS#:68247-85-8
Chemical Formula:C61H88N18O21S2
Molecular Weight:1473.58942
Peplomycin MSDSPeplomycin CoA

IUPAC/Chemical name: (2R,3S,4S,5R,6R)-2-(((2R,3S,4S,5S,6S)-2-(2-(6-amino-2-(3-amino-1-((2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidine-4-carboxamido)-3-((3-hydroxy-5-((3-hydroxy-1-oxo-1-((2-(4-((3-(((S)-1-phenylethyl)amino)propyl)carbamoyl)-[2,4'-bithiazol]-2'-yl)ethyl)amino)butan-2-yl)amino)-4-methyl-5-oxopentan-2-yl)amino)-1-(1H-imidazol-5-yl)-3-oxopropoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl carbamate
Canonical SMILES:
Reference





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