Raltitrexed( Purity > 99% by HPLC)

Product Name: Raltitrexed
 CAT#: A-2204

Request Raltitrexed
 Synonym:US brand name: Tomudex. Abbreviation: TDX. Code names: D1694; ICI-D1694; ZD1694. ,

Raltitrexed Chemical Structure
Raltitrexedchemical structure

5 stars, based on 1836 reviews

IUPAC/Chemical name:

Price of Raltitrexed

We offer a substantial discount on larger orders,
please inquire via sales@activebiochem.com
or Fax: 1-201-884-1288 (USA Fax#)


Biological Activity
Raltitrexed (Tomudex, TDX, ZD 1694) is an antimetabolite drug used in cancer chemotherapy. It is an inhibitor of thymidylate synthase, and is manufactured by AstraZeneca. Used in treatment of colorectal cancer since 1998. Raltitrexed is a quinazoline folate analogue with antineoplastic activity. After transport into cells via the reduced folate carrier, raltitrexed undergoes intracellular polyglutamation and blocks the folate-binding site of thymidylate synthase, thereby inhibiting tetrahydrofolate activity and DNA replication and repair and resulting in cytotoxicity.
Technical Data

Purity: >99%
CAS#:112887-68-0
Chemical Formula:C21H22N4O6S
Molecular Weight:458.49
Raltitrexed MSDSRaltitrexed CoA

IUPAC/Chemical name:(S)-2-(5-(methyl((2-methyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)amino)thiophene-2-carboxamido)pentanedioic acid
Canonical SMILES:
Reference





Purchase(buy) Raltitrexed at Active Biochem and the United State(U.S.), Germany, Japan, France,United Kingdom(UK),Switzerland, Australia distributors.