Talaporfin Sodium( Purity > 99% by HPLC)

Product Name: Talaporfin Sodium
 CAT#: A-2218

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 Synonym:LS11??Pe6??ono-L-aspartyl chlorin e6??aserphyrin??ono-L-aspartyl chlorin e6??S-11??E-2906 ,

Talaporfin Sodium Chemical Structure
Talaporfin  Sodiumchemical structure

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IUPAC/Chemical name:

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Biological Activity
Talaporfin sodium is a natural chlorophyll-based, and water soluble PDT photosensitizer consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, talaporfin sodium forms an extended high energy conformational state that generates singlet oxygen, which can kill target tissues with minimal side effects through vascular closure and apoptosis. Constant illumination can activate each molecule of talaporfin many times, resulting in a continuous supply of singlet oxygen molecules. Talaporfin kills all tumour cells in the targeted zone, rather than only the minority of cells undergoing rapid division, as in the case of chemotherapy. There are no serious toxicities to date. Talaporfin sodium was approved in 2004 in Japan, and is currently in phase III trials in USA
Technical Data

Purity: >99%
CAS#:220201-34-3
Chemical Formula:C38H37N5Na4O9
Molecular Weight:799.69
Talaporfin Sodium MSDSTalaporfin Sodium CoA

IUPAC/Chemical name:N-[2-[(7S,8S)-3-Carboxy-7-(2-carboxyethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-21H,23H-porphin-5-yl]acetyl]-L-aspartic acid , tetrasodium.
Canonical SMILES:
Reference





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