Product Name: TemoporfinRequest Temoporfin
Synonym: m-THPC; mTHPC; EF 9; KW-2345; KW2345; KW 2345; 3,??',??'',??'''-??7,??-??ihydroporphyrin-??,??0,??5,??0-??etrayl)??etraphenol; 5,??0,??5,??0-??etra(m-??ydroxyphenyl)??hlorin; 5,??0,??5,??0-??etrakis( ,
Temoporfin Chemical Structure
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Biological Activity Temoporfin, also known as m-THPC or KW-2345, is a synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size.
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