Thalidomide( Purity > 99% by HPLC)

Product Name: Thalidomide
 CAT#: A-2229

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 Synonym: alpha-phthalimidoglutarimide. N-phthaloylglutamimide; N-phthalylglutamic acid imide. US brand names: Synovir; Thalomid. Foreign brand names: Contergan; Distaval; Kevadon; Neurosedyn; Pantosediv; Sed ,

Thalidomide Chemical Structure
Thalidomidechemical structure

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IUPAC/Chemical name:

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Biological Activity
Thalidomide is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.
Technical Data

Purity: >99%
CAS#: 50-35-1
Chemical Formula:C13H10N2O4
Molecular Weight:258.23
Thalidomide MSDSThalidomide CoA

IUPAC/Chemical name:2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Canonical SMILES:

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