Product Name: Tropisetron HClRequest Tropisetron HCl
Synonym: ICS-205930; ICS 205930; ICS205930; ICS 205-930; ICS-205-930; Tropisetron; Tropisetron HCl; Brand name Navoban. ,
Tropisetron HCl Chemical Structure
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Biological ActivityTropisetron (INN) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. The drug is available in a 5 mg oral preparation or in 2 mg intravenous form. It is marketed by Novartis in Europe, Australia, New Zealand, Japan, South Korea and the Philippines as Navoban, but is not available in the U.S. It is also available from Novell Pharmaceutical Laboratories and marketed in several Asian countries as Setrovel.
IUPAC/Chemical name:(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1-methyl-1H-indole-3-carboxylate hydrochloride
Canonical SMILES: O=C(C1=CN(C)C2=C1C=CC=C2)OC3C[C@@H](N4C)CC[C@H]4C3.[H]Cl
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