Verteporfin( Purity > 99% by HPLC)

Product Name: Verteporfin
 CAT#: A-2245

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 Synonym:Brand name: Visudyne. Code name: DB00460; CL 318,952; Benzoporphyrin D; Bpd-MA; AIDS350621; AIDS-350621; Benzoporphyrin derivative monoacid ring A. ,

Verteporfin Chemical Structure
Verteporfinchemical structure

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IUPAC/Chemical name:

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Biological Activity
Verteporfin (trade name Visudyne), also known as Benzoporphyrin derivative monoacid ring A or BPD-MA, is a benzoporphyrin derivative and is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels. Verteporfin is also used off-label for the treatment of central serous retinopathy.
Technical Data

Purity: >99%
CAS#: 129497-78-5
Chemical Formula:C41H42N4O8
Molecular Weight:718.79
Verteporfin MSDSVerteporfin CoA

IUPAC/Chemical name:(1): 3-[(23S,24R)-14-ethenyl-5-(3-methoxy-3-oxopropyl)-22,23-bis(methoxycarbonyl)-4,10,15,24-tetramethyl-25,26,27,28-tetraazahexacyclo[,6.18,11.113,16.019,24]octacosa-1,3,5,7,9,11(27),12,14,16,18(25),19,21-dodecaen-9-yl]propanoic acid. (2): 9-methyl (I) and 13-methyl (II) trans-(? )-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-23H, 25H-benzo[b]porphine-9,13-dipropanoate.
Canonical SMILES:O=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[C@]6(C)[C@H](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5.

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