Vincristine sulfate( Purity > 99% by HPLC)

Product Name: Vincristine sulfate
 CAT#: A-2247

Request Vincristine sulfate
 Synonym:leurocristine sulfate. Brand name: Vincasar PFS; Oncovin. Abbreviation: VCR ,

Vincristine sulfate Chemical Structure
Vincristine sulfatechemical structure

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IUPAC/Chemical name:

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Biological Activity
Vincristine sulfate is the sulfate salt of a natural alkaloid isolated from the plant Vinca rosea Linn with antimitotic and antineoplastic activities. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
Technical Data

Purity: >99%
CAS#:2068-78-2
Chemical Formula:C46H58N4O14S
Molecular Weight:923.04
Vincristine sulfate MSDSVincristine sulfate CoA

IUPAC/Chemical name:(3aR,3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-((3S,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate sulfate.
Canonical SMILES:
Reference





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