Vincristine( Purity > 99% by HPLC)

Product Name: Vincristine
 CAT#: A-2248

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 Synonym: leurocristine sulfate. Brand name: Vincasar PFS; Oncovin. Abbreviation: VCR. ,

Vincristine Chemical Structure
Vincristinechemical structure

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IUPAC/Chemical name:

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Biological Activity
vincristine is a natural alkaloid isolated from the plant Vinca rosea Linn with antimitotic and antineoplastic activities. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
Technical Data

Purity: >99%
CAS#:55-22-7
Chemical Formula:C46H56N4O10
Molecular Weight:824.96
Vincristine MSDSVincristine CoA

IUPAC/Chemical name:(3aR,3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-((3S,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate.
Canonical SMILES:
Reference





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